Curiculum Vitae
Gerit Arne Linneweber
Linneweber Group • Department of Biology, Chemistry, Pharmacy (fu-berlin.de)
Freie Universität Berlin
Institute of Biology
Königin-Luise-Straße 1-3
14195 Berlin
Email: gerit.linneweber@fu-berlin.de
Telephone: +49 30 838 63080
PUBLICATIONS
Gerit Linneweber on Google Scholar
2024
Matsliah A, Yu SC, Kruk K, Bland D, Burke A, Gager J, Hebditch J, Silverman B, Willie K, Willie RW, Sorek M, Sterling AR, Kind E, Garner D, Sancer G, Wernet MF, Kim SS, Murthy M, Seung HS; FlyWire Consortium* (2024). “Neuronal parts list and wiring diagram for a visual system”. Nature 634, 166–180 (2024). https://doi.org/10.1038/s41586-024-07981-1
Schlegel P, Yin Y, Bates AS, Dorkenwald S, Eichler K, Brooks P, Han DS, Gkantia M, Dos Santos M, Munnelly EJ, Badalamente G, Capdevila LS, Sane VA, Pleijzier MW, Tamimi IFM, Dunne CR, Salgarella I, Javier A, Fang S, Perlman E, Kazimiers T, Jagannathan SR, Matsliah A, Sterling AR, Yu SC, McKellar CE; FlyWire Consortium*; Costa M, Seung HS, Murthy M, Hartenstein V, Bock DD, Jefferis GSXE (2024). “Whole-brain annotation and multi-connectome cell typing of Drosophila“. Nature 634, 139–152 (2024). https://doi.org/10.1038/s41586-024-07686-5
Dorkenwald S, Matsliah A, Sterling AR, Schlegel P, Yu SC, McKellar CE, Lin A, Costa M, Eichler K, Yin Y, Silversmith W, Schneider-Mizell C, Jordan CS, Brittain D, Halageri A, Kuehner K, Ogedengbe O, Morey R, Gager J, Kruk K, Perlman E, Yang R, Deutsch D, Bland D, Sorek M, Lu R, Macrina T, Lee K, Bae JA, Mu S, Nehoran B, Mitchell E, Popovych S, Wu J, Jia Z, Castro M, Kemnitz N, Ih D, Bates AS, Eckstein N, Funke J, Collman F, Bock DD, Jefferis GSXE, Seung HS, Murthy M; FlyWire Consortium* (2024). “Neuronal wiring diagram of an adult brain”. Nature 634, 124–138 (2024). https://doi.org/10.1038/s41586-024-07558-y
Mathejczyk TF, Knief C, Haidar MA, Freitag F, McClary T, Wernet MF, Linneweber GA (2024), “Individuality across environmental context in Drosophila melanogaster.” eLife 13:RP9817 https://doi.org/10.7554/eLife.98171.1
2023
Matsliah A, Yu SC, Kruk K, Bland D, Burke A, Gager J, Hebditch J, Silverman B, Willie K, Willie RW, Sorek M, Sterling AR, Kind E, Garner D, Sancer G, Wernet MF, Kim SS, Murthy M, Seung HS; FlyWire Consortium* (2023). Neuronal “parts list” and wiring diagram for a visual system. bioRxiv [Preprint]. 2024 Apr 15:2023.10.12.562119. doi: https://doi.org/10.1101/2023.10.12.562119.
Schlegel P, Yin Y, Bates AS, Dorkenwald S, Eichler K, Brooks P, Han DS, Gkantia M, Dos Santos M, Munnelly EJ, Badalamente G, Capdevila LS, Sane VA, Pleijzier MW, Tamimi IFM, Dunne CR, Salgarella I, Javier A, Fang S, Perlman E, Kazimiers T, Jagannathan SR, Matsliah A, Sterling AR, Yu SC, McKellar CE; FlyWire Consortium*; Costa M, Seung HS, Murthy M, Hartenstein V, Bock DD, Jefferis GSXE (2023). “Whole-brain annotation and multi-connectome cell typing quantifies circuit stereotypy in Drosophila“. bioRxiv [Preprint]. 2023 Jul 15:2023.06.27.546055. doi: https://doi.org/10.1101/2023.06.27.546055.
Dorkenwald S, Matsliah A, Sterling AR, Schlegel P, Yu SC, McKellar CE, Lin A, Costa M, Eichler K, Yin Y, Silversmith W, Schneider-Mizell C, Jordan CS, Brittain D, Halageri A, Kuehner K, Ogedengbe O, Morey R, Gager J, Kruk K, Perlman E, Yang R, Deutsch D, Bland D, Sorek M, Lu R, Macrina T, Lee K, Bae JA, Mu S, Nehoran B, Mitchell E, Popovych S, Wu J, Jia Z, Castro M, Kemnitz N, Ih D, Bates AS, Eckstein N, Funke J, Collman F, Bock DD, Jefferis GSXE, Seung HS, Murthy M; FlyWire Consortium* (2023), “Neuronal wiring diagram of an adult brain”. bioRxiv [Preprint]. 2023 Jul 11:2023.06.27.546656. doi: https://doi.org/10.1101/2023.06.27.546656.
*as part of the FlyWire Consortium
Mathejczyk TF, Knief C, Haidar MA, Freitag F, McClary T, Wernet MF, Linneweber GA (2023). Individuality across environmental context in Drosophila melanogaster. bioRxiv; 2023. DOI: https://doi.org/10.1101/2023.11.26.568741.
Dutta SB, Linneweber GA, Andriatsilavo M, Hiesinger PR, Hassan BA (2023). EGFR-dependent suppression of synaptic autophagy is required for neuronal circuit development. Current Biology 33 (3), https://doi.org/10.1016/j.cub.2022.12.039.
2022
Dutta SB, Linneweber GA., Andriatsilavo M, Hiesinger PR, Hassan BA (2022). A critical developmental interval of coupling axon branching to synaptic degradation during neural circuit formation. biorxiv, doi: https://doi.org/10.1101/2022.04.06.486606
2021
Kiral FR, Dutta SB, Linneweber GA., Hilgert S, Poppa C, Duch, C von Kleist M, Hassan BA, Hiesinger PR (2021). Brain connectivity inversely scales with developmental temperature in Drosophila. Cell reports 37 (12) DOI: 10.1016/j.celrep.2021.110145
Kohrs FE, Daumann I-M, Pavlovic B, Jin EJ, Kiral FR, Lin SC, Port F, Wolfenberg H, Mathejczyk TF, Linneweber GA, Chan C-C, Boutros M, Hiesinger PR (2021). Systematic functional analysis of Rab GTPases reveals limits of neuronal robustness to environmental challenges in flies. eLife, 2021;10:e59594 DOI: 10.7554/eLife.59594
Linneweber GA (2021) What makes us different – chance in brain development and its consequences for individuality. TheScienceBreaker 7(1). https://doi.org/10.25250/thescbr.brk451
Kiral FR, Dutta SB, Linneweber GA., Hilgert S, Poppa C, Duch, C von Kleist M, Hassan BA, Hiesinger PR (2021) “Variable brain wiring through scalable and relative synapse formation in Drosophila.” biorxiv, doi: https://doi.org/10.1101/2021.05.12.443860
2020
Linneweber GA, Andriatsilavo M, Bias Dutta S, Bengochea M, Hellbruegge L, Liu G, Ejsmont RK, Straw AD, Wernet N, Hiesinger PR, Hassan BA (2020), “A neurodevelopmental origin of behavioral individuality in the Drosophila visual system” Science 367(6482), 1112-1119, DOI: 10.1126/science.aaw7182
Kiral FR, Linneweber GA, Mathejczyk T, Georgiev SV, Wernet MF, Hassan BA, von Kleist M, Hiesinger PR (2020), “Autophagy-dependent filopodial kinetics restrict synaptic partner choice during Drosophila brain wiring.” Nat Commun. 2020 Mar 12;11(1):1325. doi: 10.1038/s41467-020-14781-4.
2019
Linneweber GA, Andriatsilavo M, Bias Dutta S, Hellbruegge L, Liu G, Ejsmont RK, Straw AD, Wernet N, Hiesinger PR, Hassan BA (2019), “A neurodevelopmental origin of behavioral individuality in the Drosophila visual system” biorxiv, https://doi.org/10.1101/540880
Kiral FR, Linneweber GA, Mathejczyk T, Georgiev SV, Wernet MF, Hassan BA, von Kleist M, Hiesinger PR (2019), “Autophagy-dependent filopodial kinetics restrict synaptic partner choice during Drosophila brain wiring” biorxiv, https://doi.org/10.1101/762179
2018
Liu G, Nath T, Linneweber GA, Guo, Z, Li, Z, De Backer S, Weyn B, Sneyders M, Nicasy H, Yu P, Scheunders P, Hassan BA (2018), “A novel tracking and quantitative social network analysis pipeline reveals the effects of isolation on social interaction dynamics in Drosophila“ Plos Comp Biol. 14(8): e1006410
2017
Franco LM, Okray Z, Linneweber GA, Hassan BA, Yaksi E (2017), “Reduced Lateral Inhibition Impairs Olfactory Computations and Behaviors in a Drosophila Model of Fragile X Syndrome.” Curr Biol. 2017 Apr 24;27(8):1111-1123.
2015
Linneweber GA, Winking M, Fischbach KF (2015), “The Cell Adhesion Molecules Roughest, Hibris, Kin of Irre and Sticks and Stones Are Required for Long Range Spacing of the Drosophila Wing Disc Sensory Sensilla.” PLoS One. 2015 Jun 8;10(6):e0128490
2014
Linneweber GA, Jacobson J, Busch KE, Hudry B, Christov CP, Dormann D, Yuan M, Otani T, Knust E, de Bono M, et al. (2014). “Neuronal Control of Metabolism through Nutrient-Dependent Modulation of Tracheal Branching.” Cell 156, 69-83.
Linneweber GA (2014) “Interactions between the nervous, digestive and respiratory systems in Drosophila melanogaster”, Thesis University of Cambridge
Before 2014
Talsma AD, Christov CP, Terriente-Felix A, Linneweber GA, Perea D, Wayland M, Shafer OT, Miguel-Aliaga I (2012), “Remote control of renal physiology by the intestinal neuropeptide pigment-dispersing factor in Drosophila.” Proc Natl Acad Sci U S A
Linneweber GA, Christov CP, Otani T, Recasens-Zorzo C, Miguel-Aliaga I (2012) “Control of food-related behaviours and metabolism by interactions between insulin-producing neurons and the tracheal system.” Journal of neurogenetics 26, S1-S89.
Pulver S, Cognigni P, Denholm B, Fabre C, Gu W, Linneweber G, Prieto-Godino L, Urbancic V, Zwart M, Miguel-Aliaga, I (2011), “Why flies? Inexpensive public engagement exercises to explain the value of basic biomedical research on Drosophila melanogaster.” Advances in Physiology Education 35: 384-392
Fischbach KF, Linneweber GA, Andlauer TF, Hertenstein A, Bonengel B, Chaudhary K (2009), “The irre cell recognition module (IRM) proteins.” Journal of neurogenetics 23(1):48-67
Cognigni, P., Linneweber, GA., Bailey, A., and Miguel-Aliaga, I. (2009). Development and function of visceral innervation in Drosophila. Mechanisms of Development 126, S190.
Linneweber, GA., and Fischbach, K-F (2009). IRM-proteins in wing development: Involvement in the regular spacing of sensory bristles in the anterior wing margin. Journal of neurogenetics 23, S18-S18.
EDUCATION AND WORK EXPERIENCE
• Emmy Noether Group Leader, FU Berlin, Germany 05/2021 –
• Postdoctoral Research Fellow, FU Berlin, Germany 11/2018 – 04/2021
• Marie Skłodowska-Curie Postdoctoral Fellow (IF), FU Berlin, Germany 01/2017 – 10/2018
Supervisor: Prof. Dr. B. Hassan, Prof. Dr. P.R. Hiesinger
• Marie Skłodowska-Curie Postdoctoral Fellow (IF), VIB, Leuven, Belgium 09/2016 – 12/2016
Supervisor: Prof. Dr. B. Hassan, Prof. Dr. J. deWit
• EMBO Long Term Fellow, KU Leuven, Leuven, Belgium 01/2015 – 08/2016
Supervisor: Prof. Dr. B. Hassan, Prof. Dr. J. deWit
• Postdoctoral Research Fellow, KU Leuven, Leuven, Belgium 03/2014 – 12/2014
Supervisor: Prof. Dr. B. Hassan, Prof. Dr. J. deWit
• MRC Clinical Science Centre, Imperial College, London, UK 06/2013 – 01/2014
Supervisor: Dr. I. Miguel-Aliaga
• 4 year Wellcome Trust PhD in Developmental Biology, Emmanuel College, Cambridge University, Cambridge, UK 10/2008 – 03/2014
Interactions between the nervous digestive and respiratory systems in Drosophila melanogaster
Supervisor: Dr. I. Miguel-Aliaga, examiners: Dr. C. O’Kane, Prof. Dr. B. Lemaitre
• MPhil, Developmental Biology, Cambridge University, Cambridge, UK 10/2008 – 10/2009
• Lab rotation Department of Physiology Development and Neuroscience and Cambridge Systems Biology Centre, University of Cambridge, Cambridge UK 03/2009 – 06/2009
Supervisor: Prof. Dr. S. Bray and Dr. B. Adryan
• Lab rotation Department of Zoology, University of Cambridge, Cambridge UK 01/2009 – 03/2009
Supervisor: Dr. I. Miguel-Aliaga
• Lab rotation Gurdon Institute, University of Cambridge, Cambridge UK 10/2008 – 01/2009
Supervisor: Dr. E. Miska
• ELTEM – Neurex Winterschool in Neurogenomics: Microarrays, q-PCR 12/2007
• Albert-Ludwigs-University, Freiburg, Germany 10/2001 – 12/2007
Degree “Diplom”, (very good), programme: Biology
Neurobiology and Biophysics, (good), examiner: Prof. Dr. K.-F. Fischbach
Evolution biology and Ecology, (very good), examiner: Prof. Dr. G. Bauer
Bioinformatics, (very good), examiner: Prof. Dr. R. Reski
Informatics, (very good), examiner: Prof. Dr. T. Ottmann, Prof. Dr. W. Burgard
• Practical training at the Dana-Farber-Cancer-Institute / HMS, Boston, USA 06/2006 – 09/2006
Department of Cancer Biology, laboratory: Prof. Dr. D. Schmucker
• Practical training at the Albert-Ludwigs-University, Freiburg, Germany 09/2005 – 10/2005
Institute Biology 3, laboratory: Prof. Dr. K.-F. Fischbach
• Practical training at the Albert-Ludwigs-University, Freiburg, Germany 04/2005 – 05/2005
AG Hirnforschung, laboratory: Prof. Dr. B. Fischer
• University of Sussex, Brighton, UK 10/2003 – 06/2004
Degree “Visiting and Exchange”, (very good), programme: Life Sciences
• Albert-Ludwigs-University, Freiburg, Germany 10/2001 – 10/2003
Degree “Vordiplom”, programme: Biology
• Helene-Lange-Gymnasium, Hamburg, Germany; A-level: (very good) 08/1991 – 06/2000
HONOURS AND AWARDS
• DFG Emmy Noether Programme (1.9 Million EUR) 09/2020
• EMBO Lab Leadership Course 06/2017
• Finalist Royal Microscopical Society Scientific Image competition 07/2015
• Genetics Society of America Drosophila Image Award 2015 02/2015
• Marie Sklodowska-Curie actions Individual Fellowship awardee 02/2015
• EMBO Long-Term Fellowship 01/2015 – present
• Cambridge University, Graduate School of Life Sciences, 3rd prize Scientific Image Competition 03/2014
• Scholarship Department of Zoology, University of Cambridge, UK 11/2012 – 06/2013
• Wellcome Trust PhD Scholarship: Cambridge University, UK, 4 year PhD programme in Developmental Biology 10/2008 – 10/2012
• Cambridge University, Graduate School of Life Sciences, 2nd prize Impact and Public Awareness Posters 03/2012
• Travel grant BSDB, Bangalore Maggot Meeting: Neural Circuits to Behaviour 07/2010
• Travel grant BSDB, BSDB/ISDB Meeting Edinburgh 09/2009
• Scholarship of the Albert-Ludwigs-University Freiburg 01/2008 – 10/2008
CONFERENCES, TEACHING AND PUBLIC AWARENESS
• Invited talk, NWG Meeting 2021, Göttingen, Germany 03/2021
• Course lecturer: Bachelor Bioinformatics, FU Berlin, Berlin, Germany 10/2019 –
• Course lecturer: Master Bioinformatics, FU Berlin, Berlin, Germany 03/2018 –
• Substitution lecturer: Bachelor/Master, FU Berlin, Berlin, Germany 01/2018 –
• Talk, EMBO Fellows Meeting 2017, Heidelberg, Germany 06/2017
• Supervision, Bachelor and Master students, FU Berlin, Berlin, Germany 01/2017 –
• Talk, German Drosophila Meeting 2016, Cologne, Germany 04/2016
• Talk, CSH Circuit Meeting 2016, Cold Spring Harbour, USA 04/2016
• Oral presentation, London Fly Meeting, London, UK 01/2014
Will branch for food
• Oral presentation, EDRC 2013, Barcelona, Spain 10/2013
Nutrient-responsive neurons control metabolism through organ-specific regulation of tracheal growth
• Oral presentation, GFE Summer School 2012, Germany 09/2012
Control of food-related behaviours and metabolism by interactions between insulin-producing neurons and the tracheal system
• Oral presentation, Neurofly 2012, Padua, Italy 09/2012
Control of food-related behaviours and metabolism by interactions between insulin-producing neurons and the tracheal system
• Supervision, MSc Student 01/2012 – 07/2012
• Supervision, 4 year Wellcome Trust rotation 10/2011 – 12/2011
• Public awareness demonstrator, Cambridge Science festival, 2011 03/2011
• Poster presentation, 2010 Bangalore Maggot Meeting, Bangalore, India 07/2010
Neuronal control of larval gut physiology
• Poster presentation, Neurofly 2008, Wuerzburg, Germany 09/2008
The involvement of IrreC/Rst, Hbs, Kirre and SNS in the regular spacing of sensory bristles in the anterior wing margin
• Supervision, practical lab training 08/2008 – 09/2008
• Lecturer and demonstrator (Substitution Prof. Dr K.-F. Fischbach), Course Biology 1B 07/2008
• Poster presentation, EDRC 2007, Vienna, Austria 09/2007
The functions of the IRM proteins in the development of sensory bristles in the wing disc of Drosophila melanogaster
• Public Awareness demonstrator, Wissenschaftsmarkt 2007, Freiburg, Germany 07/2007
• Oral and poster presentation, BCCN Neurex Meeting 2007, Freiburg, Germany 06/2007
IRM-Proteins mediate recognition of polarized cell types in muscle, sensory organ and brain development of Drosophila melanogaster
OTHER SKILLS AND WORK EXPERIENCE
• Institut für Humangenetik und Anthropologie, Freiburg, Germany 08/2002 – 08/2003
IT Coordinator
• Hilfe im Haus e.V., Hamburg, Germany 09/2000 – 08/2001
Community Service
REFERENCES
Available upon request